Ebnöther’s personal passion was comparing works from the pre-Columbian world and European and West Asian antiquity. The collector hoped that the juxtaposition of these objects would offer insight into central questions of human life.

The focus of the collection is on the New World. Some 3000 artifacts of Peruvian and Ecuadorian origin represent the most comprehensive documentation of pre-Hispanic artworks from both countries in Switzerland. A highlight is the Formative Period gold works from Peru. They are described by the renowned archaeologist Walter Alva as the largest and most important group of such finds outside the Americas.

In the Old World, the culture of the Etruscans from ancient Italy and the Urartu culture from what is now eastern Turkey are particularly well documented by outstanding objects. A large number of the objects are grave goods. The collection encompasses almost the entire range of human creativity, from simple utensils made of organic materials to elaborate objects made of precious metals.